I'd love to see more US-Eastern Europe. Maybe even UAs return to Moscow!

I think we'd also see (as far as the US3 are concerned):
AA:
MIA-tertiary South America (nonstop Asuncion, Mendoza and the like)
MIA-West Africa
JFK-Helsinki/secondary EU
PHL- see above
DFW-secondary Latin America
ORD-secondary western Europe
DL-ATL/DTW/JFK/MSP-secondary western Europe (connecting dots really, seasonal routes becoming year round)
JFK/ATL-PRG (contingent on AF/KL making their rumored team building with OK)
ATL-secondary LatAm
DTW-gru returning (the DTW crowd owes me on that one)
JFK-LED (most unlikely scenario but I see DL as more likely to go to LED than the others)
UA:
EWR-eastern Europe, maybe even year round PRG and a return to Moscow (my pipe dream)
IAD: connecting dots already served by EWR that have connection potential, West Africa (return to LOS and ACC,)
ORD: see above
*PIPEDREAM: IAD/IAH-LFE-JNB/CPT with 5th freedom rights*
IAH: return to CDG, start MAD/BCN/MXP/FCO as proposed by CO pre-787, secondary South America
SFO/LAX: maybe Fiji
*PIPEDREAM: if the govt ever allows TWOV, UA could make GUM a mean Oz-East Asia connection point*